Abstract: The aim of the present study was to investigate the effects of dietary supplementation of a compound additive prepared with composite enzymes and probiotics on growth performance and healthy status of piglets,and to provide technical references for the scientific rearing of piglets.A total of 72 piglets with initial average body weight of 8.78 kg were randomly divided into 2 groups with 3 repeats in each group and 12 piglets for each repeat.The control group fed a basal diet,and the experimental group fed the basal diet supplemented with 0.1% compound additive prepared with composite enzymes and probiotics.The results showed that the average daily gain and feed intake of the experimental group were significantly increased by 16.6%(P<0.05)and 8.4%(P<0.05)compared to the control group,respectively;the feed to gain ratio of the experimental group was significantly decreased by 7.1%(P<0.05)compared to the control group;the diarrhea rate of the experimental group was 3.11% lower than control group.The combined data suggest that the dietary supplementation of the compound additive prepared with composite enzymes and probiotics can improve the production performance and reduce diarrhea rate of piglets.