两色金鸡菊黄酮类化合物药理作用研究进展

doi:10.12160/j.issn.1672-5190.2020.04.016

Abstract

Abstract: Coreopsis tinctorial contains flavonoids, coumarins, organic acids, amino acids, saponins, volatile oils, tannins, sugars, phenols and other chemical compositions. Among them, flavonoids are the dominant compositions of Coreopsis tinctoria with the highest content. Modern pharmacology researches have found that flavonoids have many pharmacological activities, such as anti-thrombosis, anti-aging, anti-diabetes, anti-tumor, anti-antibacterial, cardioprotective, lowing blood pressure, anti-oxidative, reducing blood lipid, enhancing immune function. In this paper, the pharmacological characteristics of Coreopsis tinctoria are reviewed, in hoping to provide references for the researchers with focus on flavonoids in Coreopsis tinctoria.

Key words: Coreopsis tinctoria, pharmacological actions, flavonoids, research progress

CLC Number:

R285

ZHANG Zhen-zhen, SHA Ai-long. Research Advances on Pharmacological Actions of Flavonoids from Coreopsis tinctoria[J]. Animal Husbandry and Feed Science, 2020, 41(4): 81-84.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal30.magtechjournal.com/xmysl/EN/10.12160/j.issn.1672-5190.2020.04.016

https://journal30.magtechjournal.com/xmysl/EN/Y2020/V41/I4/81

References 30

[1]	明婷,庞市宾,哈木拉提,等.金鸡菊提取物对微循环及抗凝血作用的实验研究[J].农垦医学,2012,34(1):17-19.
[2]	王敬伟,张永威,李新霞,等.奥卡宁的提取分离及抗血小板聚集作用研究[J].新疆医科大学学报,2018,41(12):1535-1538.
[3]	杨强,孙玉华,哈木拉提.金鸡菊对大鼠主动脉的舒张作用及钾通道机制[J].中药药理与临床,2014,30(1):70-73.
[4]	凌冰,张兰兰,哈木拉提,等.金鸡菊黄酮对高血压小鼠的血压和肾素—血管紧张素系统的影响[J].中药药理与临床,2013,29(2):80-83.
[5]	梁淑红,庞市宾,刘晓燕,等.金鸡菊提取物降血脂作用的动物实验研究[J].农垦医学,2009,31(6):495-498.
[6]	谢贵林,李雅丽,刘江云,等.雪菊对胆固醇合成的影响及分子机制研究[J].新中医,2015,47(4):269-272.
[7]	LI Y,CHEN X,XUE J,et al.Flavonoids furom Coreopsis tinctoria adjust lipid metabolism in hyperlipidemia animals by down-regulating adipose differentiation-related protein[J].Lipids in Health and Disease,2014(13):193.
[8]	曾晓漫,贺晓云.昆仑雪菊的化学成分与功效研究进展[J].食品工业科技,2019,40(13):335-339.
[9]	张雅,方贺,李佳,等.两色金鸡菊总黄酮对大鼠心肌缺血再灌注损伤保护作用的研究[J].石河子大学学报(自然科学版),2016,34(1):69-73.
[10]	康宏玲,杨玉红,康宗利.昆仑雪菊总黄酮的提取及抑菌和抗氧化分析[J].食品科技,2018,43(6):236-241.
[11]	CHEUNG V W,XUE B,HERNANDEZ-VALLADARES M,et al.Identification of polyketide inhibitors targeting 3-dehydroquinate dehydratase in the shikimate pathway of Enterococcus faecalis[J].PLoS One,2014,9(7): e103598.
[12]	沙爱龙,吴瑛,盛海燕,等.昆仑雪菊黄酮对衰老模型小鼠脑及脏器指数的影响[J].动物医学进展,2013,34(7):66-68.
[13]	田勇,周督,邹双忆,等.昆仑雪菊水溶性黄酮提取物对D-半乳糖致衰老小鼠学习记忆障碍的改善作用[J].食品科学,2019,40(1):162-168.
[14]	张鑫,杨英杰,吕庆章.4种甘草黄酮类化合物抗氧化活性的密度泛函理论研究[J].计算机与应用化学,2012,29(6):656-660.
[15]	谢湖均,雷群芳,方文军.槲皮素抗氧化活性的密度泛函理论研究[J].化学学报,2010,68(15):1467-1472.
[16]	LAN S,LIN J,ZHENG N.Evaluation of the antioxidant activity of Coreopsis tinctoria Nuff. and optimisation of isolation by response surface methodology[J].Acta Pharmaceutica,2014,64(3):369-378.
[17]	丁豪,苏里阳,王文君,等.昆仑雪菊中5个黄酮类化合物抗氧化活性的DFT研究[J].农产品加工,2016(11):1-4.
[18]	丁豪,杨海燕,辛志宏.昆仑雪菊黄酮类化合物的抗氧化相互作用研究[J].食品科学,2015,36(21):26-32.
[19]	JING S,ZHANG X,YAN L J.Antioxidant activity, antitumor effect, and antiaging property of proanthocyanidins extracted from Kunlun Chrysanthemum flowers[J].Oxidative Medicine and Cellular Longevity,2015:983484.
[20]	张燕,李琳琳,木合布力·阿布力孜,等.新疆昆仑雪菊5种提取物对α-葡萄糖苷酶活性的影响[J].中国实验方剂学杂志,2011,17(7):166-169.
[21]	DIAS T,BRONZE M R,HOUGHTON P J,et al.The flavonoid-rich fraction of Coreopsis tinctoria promotes glucose tolerance regain through pancreatic function recovery in streptozotocin-induced glucose-intolerant rats[J].Journal of Ethnopharmacology,2010,132(2):483-490.
[22]	DIAS T,LIU B,JONES P,et al.Cytoprotective effect of Coreopsis tinctoria extracts and flavonoids on tBHP and cytokine-induced cell injury in pancreatic MIN6 cells[J].Journal of Ethnopharmacology,2012,139(2):485-492.
[23]	JIANG B,LE L,LIU H,et al.Marein protects against methylglyoxal-induced apoptosis by activating the AMPK pathway in PC12 cells[J].Free Radical Research,2016,50(11):1173-1187.
[24]	JIANG B,LE L,ZHAI W,et al.Protective effects of marein on high glucose-induced glucose metabolic disorder in HepG2 cells[J].Phytomedicine,2016,23(9):891-900.
[25]	刘菁,姚蓝,毕晓娟,等.两色金鸡菊黄酮成分马里苷对胰岛β细胞的保护作用[J].新疆医科大学学报,2017,40(4):428-432.
[26]	阳敦学,彭秀达,卢先州.雪菊药理作用的研究进展[J].湘南学院学报(医学版),2019,21(2):75-78.
[27]	帕尔哈提·买买提依明,令狐晨,朱青梅,等.昆仑雪菊对结肠癌细胞株体外抗肿瘤作用研究[J].安徽农业科学,2015,43(20):146-148.
[28]	帕尔哈提·买买提依明,令狐晨,朱青梅,等.雪菊对肝癌和肺癌细胞体外抗肿瘤作用研究[J].安徽农业科学,2015,43(24):46-48.
[29]	杨杰,沙金丹,高翔,等.黄酮类化合物的免疫调节作用及机制[J].动物营养学报,2017,29(12):4295-4300.
[30]	秦乐,陈新梅,邢佰颖,等.昆仑雪菊总黄酮对小鼠胸腺指数及脾脏指数的影响[J].山东化工,2017,46(15):41-42.

Research Advances on Pharmacological Actions of Flavonoids from Coreopsis tinctoria

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References 30

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	ZHANG Jiansheng, ZHU Yuanfang, HAI Long, NAN Jingdong, CHEN Guowang, HAO Caihong, JIA Bin, ZHANG Bei, WANG Likun, ZHANG Guohua, SHEN Sisi. Research Progress on the Action Mechanisms of Probiotics and Their Application in Swine Production [J]. Animal Husbandry and Feed Science, 2024, 45(2): 29-34.
[2]	ZHANG Qingqing, LIU Xuejiao, ZHANG Bo, ZHANG Peng, HE Jia, HAN Haibo, Chao Lemeng, ZHENG Shuhua. CiteSpace Based Analysis of Research Hotspots and Evolution Trend of Grassland Ecological Protection Compensation in China [J]. Animal Husbandry and Feed Science, 2024, 45(2): 50-57.
[3]	HAI Tingyu, JIN Kexu, ELMYRA Abduwali, FENG Haoqiang, DAI Xiaohua. Impacts of Different Procedures on the Extraction of Total Flavonoids from Chickpea（Cicer arietinum）and the Analgesic Effect on Mice [J]. Animal Husbandry and Feed Science, 2024, 45(2): 88-94.
[4]	GUO Yuan-yin, SHU Jia-min, HOU Yu-fei, DING Yu, WANG Jian-nan, SONG Cun-tao, Aygul , DAI Xiao-hua. Effects of Total Flavonoids from Wild Apricot on Slaughter Performance of Sanhuang Broiler Chickens [J]. Animal Husbandry and Feed Science, 2022, 43(6): 36-41.
[5]	SHI Xin-rui, CHEN Ying-kai, CHEN Zhong-ting, ZHAO Wei-dan, JIANG Ming-sheng, CHEN Hai-lan. Protective Effects of Total Flavonoids from Spatholobus suberectus Dunn on Liver Injury Induced by Cyclophosphamide in Mice [J]. Animal Husbandry and Feed Science, 2022, 43(4): 8-13.
[6]	YANG Ding, Yeruhan, LI Chang-qing, WANG Hui-min, TIAN Feng, SUN Hai-lian, YI Feng-yan. Research Advances on the Effects of Quercetin and Other Flavonoids on Rumen Microorganisms [J]. Animal Husbandry and Feed Science, 2020, 41(6): 32-36.
[7]	SU Hong, ZHI Da-fu, YANG Guang, WANG Tong, TIAN Zhi-peng, CAO Gui-fang. Advances in Research on the Important Role of Brachyury Gene during Embryonic Development [J]. Animal Husbandry and Feed Science, 2020, 41(2): 13-16.
[8]	Amuguleng, PEI Le, LI Feng, GENG Wan-heng, HOU Yong-yue, LU Yan, LI Zi-jian, LIU Xiu-li. Effect of Ultrasound-assisted Extraction on Total Flavonoids Content in Radix scutellariae [J]. Animal Husbandry and Feed Science, 2020, 41(1): 73-76.
[9]	LIU Chang, Tumenbayaer, LU Zhen-xiang, NING Kang-jian, JIANG Jin-peng, LI Lei. Research Progress on Poultry Ankara Disease [J]. Animal Husbandry and Feed Science, 2019, 40(8): 107-109.
[10]	CHEN Yu, CHEN Wei, LI Feng-tao, MA Lan. Research Progress on Chemical Constituents and Pharmacological Actions of Cyclocarya paliurus [J]. Animal Husbandry and Feed Science, 2019, 40(12): 61-63.
[11]	LV Hong-chao, WANG Hui, CHENG Xiao-guo, MA Jing-xia. Research Progress on Vaccines of Chicken Infectious Coryza [J]. Animal Husbandry and Feed Science, 2019, 40(12): 98-101.
[12]	. Optimization of Extraction Process of Total Flavonoids from Artemisia frigida,a Traditional Mongolian Medicine [J]. Animal Husbandry and Feed Science, 2018, 39(7): 26-26.
[13]	. Research Progress on Pharmacology and Clinical Applications of Glycoalkaloids [J]. Animal Husbandry and Feed Science, 2018, 39(6): 78-78.
[14]	. Research Progress on Flavonoids in Scutellaria baicalensis [J]. Animal Husbandry and Feed Science, 2018, 39(5): 71-71.
[15]	. Advances in Seeds Physiology of Ceratoides [J]. Animal Husbandry and Feed Science, 2018, 39(3): 55-55.