群体感应系统调控细菌生物膜的研究进展

doi:10.12160/j.issn.1672-5190.2020.05.002

Abstract

Abstract: This paper introduces the bacterial biofilm and its formation process, describes the conception of bacterial quorum sensing （QS） system, and expounds four types of regulative mechanism of QS system, including the AHL-LuxI/LuxR based QS system in Gram-negative bacteria, the QS system in Gram-positive bacteria, the LuxS/AI-2 mediated interspecific QS system, and the AI-3/ epinephrine/norepinephrine signaling system. The roles of QS system in bacteria and its regulative mechanism in formation of bacterial biofilm are elaborated, in hoping to provide references for the development of lactic acid bacteria agents and the investigations on antimicrobial resistance of pathogenic bacteria.

Key words: bacterial biofilm, quorum sensing, lactic acid bacteria, pathogenic bacteria

CLC Number:

Q935

ZHONG Hua-chen, HE Yin-feng. Research Advances on Regulative Role of Quorum Sensing System in Formation of Bacterial Biofilm[J]. Animal Husbandry and Feed Science, 2020, 41(5): 7-12.

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References

[1] SOTO S M.Role of efflux pumps in the antibiotic resistance of bacteria embedded in a biofilm[J]. Virulence, 2013, 4(3):223-229 .
[2] JAMAL M, AHMAD W, ANDLEEB S, et al.Bacterial biofilm and associated infections[J].Journal of the Chinese Medical Association, 2018, 81(1):7-11.
[3] 薛挺. 大肠杆菌及金黄色葡萄球菌AI-2群体感应系统的调控研究[D].北京:中国科学技术大学, 2009.
[4] FAZLI M, ALMBLAD H, RYBTKE M L, et al.Regulation of biofilm formation in Pseudomonas and Burkholderias pecies[J].Environmental Microbiology, 2014, 16(7):1961-1981.
[5] 李博. 不同生理环境胁迫对乳酸菌产信号分子AI-2影响的研究[D].呼和浩特:内蒙古农业大学, 2016.
[6] SCUTERA S, ZUCCA M, SAVOIA D.Novel approaches for the design and discovery of quorum-sensing inhibitors[J].Expert Opinion on Drug Discovery, 2014, 9(4):353-366.
[7] HØIBY N, BJARNSHOLT T, GIVSKOV M, et al. Antibiotic resistance of bacterial biofilms[J]. International Journal of Antimicrobial Agents, 2010, 35(4):322-332.
[8] TRIBEDI P, SIL A K.Cell surface hydrophobicity: a key component in the degradation of polyethylene succinate by Pseudomonas sp. AKS2[J].Journal of Applied Microbiology, 2014, 116(2):295-303.
[9] SRIVASTAVA S, BHARGAVA A.Biofilms and human health[J].Biotechnology Letters, 2016, 38(1):1-22.
[10] OTTO M.Staphylococcal infections: mechanisms of biofilm maturation and detachment as critical determinants of pathogenicity[J].Annual Review of Medicine, 2013, 64:175-188.
[11] REUTER K, STEINBACH A, HELMS V.Interfering with bacterial quorum sensing[J].Perspectives in Medicinal Chemistry, 2016, 8:1-15.
[12] 郭倩茹. 共生乳酸菌酵母菌的筛选及产信号分子AI-2的研究[D].呼和浩特:内蒙古农业大学, 2015.
[13] KAPER J B, SPERANDIO V.Bacterial cell-to-cell signaling in the gastrointestinal tract[J].Infection and Immunity, 2005, 73(6): 3197-3209.
[14] 张腾. 植物乳杆菌HE-1在共培养中产抑菌物质与LuxS/AI-2群体感应现象关系的研究[J].呼和浩特: 内蒙古农业大学, 2014.
[15] LOWERY C A, DICKERSON T J, JANDA K D.Interspecies and interkingdom communication mediated by bacterial quorum sensing[J].Chemical Society Reviews, 2008, 37:1337-1346.
[16] 邵长林, 孙忠科, 廖祥儒, 等.群体感应与病原菌致病性研究进展[J].生物技术通讯, 2011, 22(3):445-448.
[17] 郭嘉亮, 陈卫民.细菌群体感应信号分子与抑制剂研究进展[J].生命科学, 2007, 19(2):225-227.
[18] QUINTO E J, JIMÉNEZ P, CARO I, et al. Probiotic lactic acid bacteria: a review[J].Food and Nutrition Sciences, 2014, 5(18):1765-1775.
[19] 姜黎明. LuxS/AI-2群体感应系统介导植物乳杆菌益生特性的初步研究[D].昆明:昆明理工大学, 2014.
[20] SHAO C, SHANG W, YANG Z, et al.LuxS-dependent AI-2 regulates versatile functions in Enterococcus faecalis V583[J].Journal of Proteome Research, 2012, 11(9):4465-4475.
[21] CHRISTIAEN S E A, O′CONNELL M M, BOTTACINI F, et al. Autoinducer-2 plays a crucial role in gut colonization and probiotic functionality of Bifidobacterium breve UCC2003[J].PLoS One, 2014, 9(5):e98111.
[22] SUN Z, HE X, BRANCACCIO V F, et al.Bifidobacteria exhibit LuxS-dependent autoinducer 2 activity and biofilm formation[J]. PLoS One, 2014, 9(2):e88260.
[23] LIU L, WU R, ZHANG J, et al .Overexpression of luxS promotes stress resistance and biofilm formation of Lactobacillus paraplantarum L-ZS9 by regulating the expression of multiple genes[J].Frontiers Microbiology, 2018, 9:2628.
[24] LEBEER S, CLAES I J J, VERHOEVEN T L A, et al.Impact of luxS and suppressor mutations on the gastrointestinal transit of Lactobacillus rhamnosus GG[J].Applied and Environmental Microbiology, 2008, 74(15):4711-4718.
[25] 蔡针华. 群体感应信号分子AI-2高产乳酸菌株筛选及特性研究[D].临汾:山西师范大学, 2018.
[26] RAO R M, PASHA S N, SOWDHAMINI R.Genome-wide survey and phylogeny of S-Ribosylhomocysteinase (LuxS) enzyme in bacterial genomes[J].BMC Genomics, 2016, 17(1): 742.
[27] WANG Y, ZHANG W, WU Z, et al.Functional analysis of luxS in Streptococcus suis reveals a key role in biofilm formation and virulence[J].Veterinary Microbiology, 2011, 152(1/2):151-160.
[28] PANG B, ARMBRUSTER C E, FOSTER G, et al.Autoinducer 2 (AI-2) production by nontypeable Haemophilus influenzae 86-028NP promotes expression of a predicted glycosyltransferase that is a determinant of biofilm maturation, prevention of dispersal, and persistence in vivo[J].Infection and Immunity, 2018, 86(12):e00506-18.
[29] LI L, ZHOU R, LI T, et al.Enhanced biofilm formation and reduced virulence of Actinobacillus pleuropneumoniae luxS mutant[J].Microbial Pathogenesis, 2008, 45(3):192-200.
[30] SCHUSTER M, URBANOWSKI M L, GREENBERG E P.Promoter specificity in Pseudomonas aeruginosa quorum sensing revealed by DNA binding of purified LasR[J].Proceedings of the National Academy of Sciences of the United States of America, 2004, 101(45):15833-15839.
[31] DAVIES D G, PARSEK M R, PEARSON J P, et al.The involvement of cell-to-cell signals in the development of a bacterial biofilm[J].Science, 1998, 280(5361):295-298.
[32] HEEB S, FLETCHER M P, CHHABRA S R, et al.Quinolones: from antibiotics to autoinducers[J].FEMS Microbiology Reviews, 2011, 35(2):247-274.
[33] 孟菲, 黎书长, 杨武宁, 等.铜绿假单胞菌生物膜研究进展[J].中国畜牧兽医, 2016, 43(11):2976-2981.
[34] QUECK S Y, JAMESON-LEE M, VILLARUZ A E, et al.RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus[J].Molecular Cell, 2008, 32(1):150-158.
[35] SOLANO C, ECHEVERZ M, LASA I.Biofilm dispersion and quorum sensing[J].Current Opinion in Microbiology, 2014, 18(4):96-104.
[36] REN D, BEDZYK L A, THOMAS S M, et al.Gene expression in Escherichia coli biofilms[J].Applied Microbiology and Biotechnology, 2004, 64(4):515-524.
[37] STURBELLE R T, DA COSTA DE AVILA L F, ROOS T B, et al. The role of quorum sensing in Escherichia coli(ETEC) virulence factors[J].Veterinary Microbiology, 2015, 180(3/4):245-252.
[38] LEE H H, MOLLA M N, CONTOR C R, et al.Bacterial charity work leads to population-wide resistance[J].Nature, 2010, 467(7311): 82-85.

Research Advances on Regulative Role of Quorum Sensing System in Formation of Bacterial Biofilm

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