Animal Husbandry and Feed Science ›› 2021, Vol. 42 ›› Issue (4): 118-123.doi: 10.12160/j.issn.1672-5190.2021.04.020

• Veterinary Pharmaceutical Science • Previous Articles     Next Articles

Effects of Total Flavonoids from Rhizoma Drynariae on Bone Metabolism and Action Mechanisms

ZHANG Chao-dong, CAO Qin-qin, XU Ting-ting, LIN Lu-xi, YUE Ke, ZHENG Jing-jing, HUANG Shu-cheng   

  1. College of Veterinary Medicine,Henan Agricultural University,Zhengzhou 450002,China
  • Received:2021-05-11 Online:2021-07-30 Published:2021-08-25

Abstract: The key to maintain the balance of bone tissue is the dynamic balance of bone metabolism. The imbalance of bone metabolism results in bone damages and even bone diseases. Total flavonoids extracted from Rhizoma Drynariae, a traditional Chinese medicine, are active ingredients that have therapeutic effects on bone diseases such as osteoporosis, bone defect, bone fracture and osteoarthritis. Based on the summary of relevant literatures in China and abroad, this paper reviews the effects of total flavonoids from Rhizoma Drynariae on bone metabolism from the aspects of bone tissue, blood vessels, bone cells and related regulatory mechanisms, in hoping to provide theoretical basis for further researches.

Key words: Rhizoma Drynariae, signaling pathways, bone metabolism, action mechanisms, traditional Chinese medicine

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