Abstract: With the acceleration of large-scale livestock and poultry farming in China, the concept of "prevention first" among livestock and poultry producers has placed higher demands on scientific disinfection practices. The scientific selection of chemical disinfectants and optimization of disinfection strategies have become critical for disease prevention and control. In this context, this paper systematically reviews the types, mechanisms of action, application methods, and development of novel chemical disinfectants commonly used in livestock and poultry, with particular focuses on summarizing the factors influencing disinfection efficacy, such as environmental temperature, pH, and organic matter load, aiming to provide a reference for the scientific selection and application of chemical disinfectants in livestock and poultry producers.

Key words: livestock and poultry farming, chemical disinfectants, mechanism of action, disinfection efficacy, influencing factors