Abstract: This study conducted compared experiments about the fertilizer effects of different combinations of nitrogen(N),phosphate(P)and potassium(K)fertilizers under high-density maize planting condition(double plants in one point)and conventional planting condition(single plant in one point).The results showed that the yields under high-density maize planting condition(double plants in one point)were higher than the yields under conventional planting(single plant in one point)of similar combinations of N,P and K fertilizers.And the yield under 4th combination of enough N,P and K fertilizers(N2P2K2)increased most.The comprehensive effect of N,P and K fertilizers under high-density maize planting condition(double plants in one point)was 42.6%higher than that under conventional planting condition(single plant in one point),and N fertilizer effect was 29.2%higher;P fertilizer effect was 22.5%higher;K fertilizer effect was 14.5%higher.And agronomic efficiency of the N,P,K fertilizers under high-density maize planting condition(double plants in one point)were 10.5 kg/kg,12.7 kg/kg and 25.8 kg/kg higher than that under conventional planting condition(single plant in one point).These results proved the fertilizer effects under high-density maize planting condition(double plants in one point)was very significant higher than those under conventional planting condition(single plant in one point).Under the experimental conditions,the utilization rate of N,P,K fertilizers under high-density maize planting condition(double plants in one point)were 8.14%,5.27%and 1.99%than that under conventional planting condition(single plant in one point),respectively.