畜牧与饲料科学 ›› 2019, Vol. 40 ›› Issue (6): 30-33.doi: 10.12160/j.issn.1672-5190.2019.06.009

• 遗传与繁育 • 上一篇    下一篇

哺乳动物雌性生殖系统β-防御素的研究进展

王东阳, 包图雅   

  1. 内蒙古医科大学基础医学院,内蒙古 呼和浩特 010100
  • 收稿日期:2019-05-06 出版日期:2019-06-30 发布日期:2019-12-25
  • 通讯作者: 包图雅(1978—),女,副教授,博士,主要从事组织胚胎学与分子生物学研究工作。
  • 作者简介:王东阳(1989—),女,硕士,主要研究方向为生殖医学。

Research Progress on Beta-defensins in Female Mammalian Reproductive System

WANG Dong-yang, Baotuya   

  1. College of Basic Medicine,Inner Mongolia Medical University,Hohhot 010100,China
  • Received:2019-05-06 Online:2019-06-30 Published:2019-12-25

摘要: β-防御素(beta-defensian,BD)在哺乳动物雌性生殖系统中广泛表达,在免疫、预防生殖道感染及胎儿正常发育等方面起到重要作用。主要对哺乳动物β-防御素在哺乳动物雌性生殖系统组织中的分布、作用及其调控进行了综述,并对其应用前景进行了展望,以期更好地揭示β-防御素在雌性生殖系统中的影响,从而为β-防御素的进一步研究提供理论依据。

关键词: β-防御素, 哺乳动物, 雌性生殖系统, 调控

Abstract: Beta-defensin has been found to be widely expressed in the female reproductive system of mammals, which plays an important role in immunity, prevention of reproductive tract infection and normal fetal development. In this paper, the distribution, function and regulation of beta-defensin in female mammalian reproductive system were reviewed, and its application was prospected, in hoping to provide references for better reveal the roles of beta-defensin in female reproductive system.

Key words: beta-defensin, mammals, female reproductive system, regulation

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