丁酸梭菌培养物对哺乳期湖羊母羊生产性能、血清生化指标及羔羊生长性能的影响

doi:10.12160/j.issn.1672-5190.2026.02.006

摘要/Abstract

摘要： [目的] 研究日粮中添加丁酸梭菌培养物对产双羔哺乳期湖羊母羊生产性能、血清生化指标及羔羊生长性能的影响。[方法] 选择同一生产批次、年龄相近、体重相近且产双羔的哺乳7 d湖羊母羊24只,及其所产的平均初生重相近、健康的双胎杜泊×湖羊杂交一代羔羊48只,随机分成4组（每组6只母羊、12只羔羊）,分别饲喂基础日粮（CK组）、基础日粮+0.1%丁酸梭菌培养物（CB1组）、基础日粮+0.2%丁酸梭菌培养物（CB2组）和基础日粮+0.4%丁酸梭菌培养物（CB4组）。试验期为53 d。分别于试验第9、24、39、53天测量母羊生产性能及羔羊生长性能指标（母羊体重分别于试验开始、结束各称量1次）,试验结束后测定母羊血清生化指标。[结果] ①丁酸梭菌培养物对母羊体重和平均日增重均无显著影响（P>0.05）,CB4组干物质采食量极显著（P<0.01）高于其他组。②丁酸梭菌培养物对母羊泌乳量和乳成分均无显著影响（P>0.05）。③丁酸梭菌培养物显著（P<0.05）提升了羔羊的生长性能,24~53 d时CB4组羔羊体重极显著（P<0.01）高于CK组,试验全阶段CB4组羔羊开食料采食量显著（P<0.05）高于CK组。④CB1组白细胞介素-2（IL-2）含量显著（P<0.05）高于CB4组,CB4组白细胞介素-6（IL-6）含量极显著（P<0.01）低于CK组; CB4组总抗氧化能力（T-AOC）、超氧化物歧化酶（SOD）活性、谷胱甘肽过氧化物酶（GSH-Px）活性极显著（P<0.01）高于CK、CB1、CB2组;丁酸梭菌培养物对血清总蛋白（TP）、白蛋白（ALB）、球蛋白（GLB）、胆固醇（TC）、三酰甘油（TG）、尿素氮（BUN）、天门冬氨酸氨基转移酶（AST）、丙氨酸氨基转移酶（ALT）、血糖（GLU）及催乳素（PRL）含量均无显著影响（P>0.05）,但CB4组孕酮（P）含量、CB2组雌激素（E2）含量显著（P<0.05）高于CK组。[结论] 日粮添加丁酸梭菌培养物虽不能显著提升母羊的体重、泌乳量及乳成分指标,但能通过多成分协同作用,极显著（P<0.01）提高试验中后期干物质采食量,调节母羊免疫与抗氧化功能,并显著（P<0.05）促进羔羊的生长性能。综合各项指标,0.4%为丁酸梭菌培养物的最佳添加剂量。

关键词: 湖羊母羊, 生产性能, 泌乳量, 血清生化指标, 羔羊生长性能

Abstract: [Objective] To investigate the effects of dietary supplementation with Clostridium butyricum culture on the production performance, serum biochemical indices of lactating Hu ewes producing twin lambs, and the growth performance of lambs. [Methods] Twenty-four lactating twin-bearing Hu ewes （7 days postpartum） from the same production batch with similar age and body weight, together with forty-eight of their healthy twin F1 Dorper × Hu crossbred lambs with similar average birth weights, were selected and randomly assigned to four groups （6 ewes and 12 lambs per group）: a basal diet （CK）, a basal diet supplemented 0.1% C. butyricum culture （CB1）, a basal diet supplemented 0.2% C. butyricum culture （CB2）, and a basal diet supplemented 0.4% C. butyricum culture （CB4）. The experimental period lasted for 53 days. Production performance indices of ewes and growth performance indices of lambs were measured on days 9, 24, 39, and 53, respectively. The body weight of ewes was measured at the start and end of the experiment. Serum biochemical indices of ewes were determined at the end of the experiment. [Results] ① C. butyricum culture had no significant effects on body weight and average daily gain of ewes （P>0.05）, but dry matter intake in the CB4 group was extremely significantly higher than that in the other groups （P<0.01）. ② C. butyricum culture had no significant effect on milk yield and milk composition of ewes （P>0.05）. ③ C. butyricum culture significantly improved growth performance of lambs （P<0.05）; body weight of lambs in the CB4 group during 24-53 days was extremely significantly higher than that in the CK group （P<0.01）, and starter feed intake of lambs in the CB4 group during the whole experimental period was significantly higher than that in the CK group （P<0.05）. ④ Interleukin-2 （IL-2） content in the CB1 group was significantly higher than that in the CB4 group （P<0.05）, and interleukin-6 （IL-6） content in the CB4 group was extremely significantly lower than that in the CK group （P<0.01）. The total antioxidant capacity （T-AOC）, superoxide dismutase （SOD） activity, and glutathione peroxidase （GSH-Px） activity in the CB4 group were extremely significantly higher than those in the CK, CB1, and CB2 groups （P<0.01）. C. butyricum culture had no significant effects on serum total protein （TP）, albumin （ALB）, globulin （GLB）, total cholesterol （TC）, triglyceride （TG）, blood urea nitrogen (BUN), aspartate aminotransferase （AST）, alanine aminotransferase （ALT）, glucose （GLU）, or prolactin （PRL） levels （P>0.05）. However, progesterone （P） content in the CB4 group and estradiol （E2） content in the CB2 group were significantly higher than those in the CK group （P<0.05）. [Conclusion] Dietary supplementation with C. butyricum culture does not significantly improve body weight, milk yield, or milk composition of ewes; however, it extremely significantly increases dry matter intake during the middle and late experimental stages through multi-component synergistic effects （P<0.01）, regulates immune and antioxidant functions of ewes, and significantly improves growth performance of lambs （P<0.05）. Considering all indices, 0.4% is the optimal supplemental level of C. butyricum culture.

Key words: Hu ewes, production performance, milk yield, serum biochemical indices, growth performance of lambs

中图分类号:

董泽华, 刘艳丰, 唐淑珍, 王文奇, 夏国鹏, 张雪, 李忠佳. 丁酸梭菌培养物对哺乳期湖羊母羊生产性能、血清生化指标及羔羊生长性能的影响[J]. 畜牧与饲料科学, 2026, 47(2): 42-50.

DONG Zehua, LIU Yanfeng, TANG Shuzhen, WANG Wenqi, XIA Guopeng, ZHANG Xue, LI Zhongjia. Effects of Clostridium butyricum Culture on Production Performance, Serum Biochemical Indices of Lactating Hu Ewes as well as Growth Performance of Their Lambs[J]. Animal Husbandry and Feed Science, 2026, 47(2): 42-50.

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