沙门菌疫苗的应用现状及研究前景

doi:10.12160/j.issn.1672-5190.2020.04.022

畜牧与饲料科学 ›› 2020, Vol. 41 ›› Issue (4): 111-114.doi: 10.12160/j.issn.1672-5190.2020.04.022

沙门菌疫苗的应用现状及研究前景

张俊霞¹, 冯永淼¹, 李蓉¹, 王利²

1.呼和浩特职业学院生物化学工程学院,内蒙古呼和浩特 010051;
2.内蒙古医科大学基础医学院,内蒙古呼和浩特 010059

收稿日期:2020-03-19 出版日期:2020-07-30 发布日期:2020-08-19
通讯作者: 王利（1981—）,男,副教授,硕士生导师,主要研究方向为医学免疫学。
作者简介:张俊霞（1981—）,女,副教授,博士,主要研究方向为生物化学与分子生物学。
基金资助:
内蒙古自治区自然科学基金项目（2018MS03080）; 呼和浩特市科技计划项目（2018-高-4）; 内蒙古自治区高等学校科学研究项目（NJZY16448）

Application Status and Research Prospects of Salmonella Vaccines

ZHANG Jun-xia¹, FENG Yong-miao¹, LI Rong¹, WANG Li²

1. School of Biochemistry Engineering,Hohhot Vocational College,Hohhot 010051,China;
2. College of Basic Medicine,Inner Mongolia Medical University ,Hohhot 010059,China

Received:2020-03-19 Online:2020-07-30 Published:2020-08-19

摘要/Abstract

摘要： 沙门菌病（salmonellosis）是由沙门菌属（Salmonella）细菌感染引起的人畜共患病。接种疫苗是预防和控制畜禽沙门菌病的有效途径。由于当前使用的沙门菌减毒疫苗成本较高,免疫效果不稳定,免疫程序复杂,导致使用率不高。口服植物型沙门菌疫苗具有产量高、生产时间短、成本低、安全性高等特点。对口服植物型沙门菌疫苗的研究前景和研究方向进行综述,以期为该类疫苗的进一步研究开发和广泛利用提供参考。

关键词: 沙门菌, 沙门菌病, 口服植物型沙门菌疫苗, 预防

Abstract: Salmonellosis is a zoonotic disease caused by bacterial infection of the Salmonella genus. Vaccination is an effective way to prevent and control salmonellosis in livestock and poultry. Due to the high cost, unstable immune effect and complicated immune procedure, the application of the currently used Salmonella attenuated vaccines is limited. Oral plant- based Salmonella vaccines have the advantages of high yield, short production time, low cost and high safety. This paper reviews the research prospects of oral plant-based Salmonella vaccines, in hoping to provide references for the further research, development and widespread application of this type of vaccines.

Key words: Salmonella, salmonellosis, oral plant-based Salmonella vaccines, prevention

中图分类号:

张俊霞, 冯永淼, 李蓉, 王利. 沙门菌疫苗的应用现状及研究前景[J]. 畜牧与饲料科学, 2020, 41(4): 111-114.

ZHANG Jun-xia, FENG Yong-miao, LI Rong, WANG Li. Application Status and Research Prospects of Salmonella Vaccines[J]. Animal Husbandry and Feed Science, 2020, 41(4): 111-114.

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沙门菌疫苗的应用现状及研究前景

Application Status and Research Prospects of Salmonella Vaccines

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