驼乳对不同类型肝损伤的保护作用研究进展

doi:10.12160/j.issn.1672-5190.2023.04.016

摘要/Abstract

摘要：

肝损伤威胁人类健康和生命安全，其致病因素较多，如药物、饮酒、糖尿病、环境应激等。动物发生肝损伤，其生产性能下降，对畜牧业生产造成较大的经济损失。氧化应激（oxidative stress, OS）及其介导的炎症反应是不同类型肝损伤的共同发病机制。驼乳（camel milk, CM）及其乳清蛋白（camel whey protein, CWP）是天然的抗氧化剂，可以通过增强机体的抗氧化能力而抑制OS的发生，因此，具有潜在的抗肝损伤功效。围绕CM和CWP的抗OS和抗炎症作用，综述了CM及CWP对化学性、酒精性、糖尿病性肝损伤以及热应激引起肝损伤的保护作用的研究进展，以期为后续相关研究提供更多线索，为推广CM的保健作用提供参考。

关键词: 肝损伤, 驼乳, 驼乳清蛋白, 氧化应激, 炎症反应

Abstract:

Liver injury threatens human health and life safety, which has various causative factors, such as drugs, alcohol, diabetes mellitus, and environmental stress. In animals, liver injury leads to decrease in production performance and results in severe economic losses in animal husbandry production. Oxidative stress （OS） and its mediated inflammatory response are the common pathogenesis of different types of liver injury. Camel milk （CM） and camel whey protein （CWP） are natural antioxidants that can prevent OS by boosting the antioxidant capacity of the body. Therefore, they have potential anti-liver damage effects. Focusing on the roles of anti-OS and anti-inflammation, the research progress in the protective effects of CM and CWP against the chemical, alcoholic and diabetes mellitus-induced liver injury as well as the heat stress-induced liver injury is reviewed, in hoping to give novel insights into the future research and provide references for promoting the health care role of CM.

Key words: liver injury, camel milk, camel whey protein, oxidative stress, inflammatory response

中图分类号:

S879.1

高天, 杜冬华, 哈斯苏荣. 驼乳对不同类型肝损伤的保护作用研究进展[J]. 畜牧与饲料科学, 2023, 44(4): 116-121.

GAO Tian, DU Donghua, Hasisurong . Research Progress in Protective Effects of Camel Milk on Different Types of Liver Injury[J]. Animal Husbandry and Feed Science, 2023, 44(4): 116-121.

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