Abstract: In order to explore the effects of Scutellaria on tension of small intestine of rabbit in vitro,Scutellaria extracts were used to act on in vitro duodenum and jejunum,and changes in tension were observed.Scutellaria decoction containing crude drug of 0.02,0.04 and 0.08 g/mL could excite smooth muscle of the duodenum and jejunum.Furthermore,the Scutellaria decoction containing crude drug of 0.08 and 0.04 g/mL had the strongest excitation on tension and motion of the duodenum;and the Scutellaria decoction containing crude drug of 0.08 g/mL had the strongest excitation on the jejunum.Scutellaria decoction extracted by ethanol containing crude drug of 0.02,0.04 and 0.08 g/mL could excite smooth muscle of the duodenum and jejunum,and that containing crude drug of 0.08 g/mL had the strongest excitation.Scutellaria extracted by different methods and containing crude drug of 0.16 g/mL had significant inhibitory effects on the duodenum and jejunum.In conclusion,low-dose Scutellaria extracts can excite smooth muscle,but high-dose Scutellaria extracts have significant inhibitory effects（P〈0.01）.Acetylcholine can excite in vitro intestine of rabbit in short time.The frequency changes were accelerated with increasing excitability of smooth muscle of small intestinal,and vice versa.