Abstract: In order to determine the appropriate dietary lysine and sulfur amino acid ratio for Rex Rabbit in late fattening period, a total of 300 3-month-old white Rex Rabbit were randomly and averagely divided into six groups. The lysine （0.80%） and sulfur amino acid （0.56%） ratio in basal diet of control group was 1：0.7 and that of experimental Ⅰ to Ⅴ group was adjust to 1：0.8, 1：0.9, 1 ： 1.0, 1 ： 1.1, 1 ： 1.2 by supplementing methionine. The experimental period lasted for 50 days; the disease incidence and mortality of Rex Rabbits in each group during the whole experiment period were observed and recorded, and the survival rate was calculated; at the end of the experiment, the hair density and hair length of Rex Rabbits in different groups were determined and statistically compared; the fur quality and market price of Rex Rabbits in different groups were evaluated and compared. The results revealed that the hair density of experimental Ⅱ group was very significantly higher than that of control group, experimental Ⅲ group and experimental Ⅴ group （P〈0.01）, and was significantly higher than that of experimental Ⅳ group （P〈 0.05 ）; the hair density of experimental I group was significantly higher than that of control group, experimental Ⅲ group and experimental V group （P〈0.05）; different dietary lysine and sulfur amino acid ratio had no significant impact on hair length of Rex Rabbit （P〉0.05）; there were 25 pieces of first-grade fur in both experimental I group and experimental Ⅱ group which were more than that in the other groups; the highest proportion （73.33%） of superior-grade fur was obtained in experimental Ⅱ group; the income from fur selling of control group, experimental Ⅲ group, experimental IV group and experimental V group was 4.75%, 8.29%, 5.70%, 13.62% less than that of experimental Ⅱ group; the highest （100%） and the lowest survival rate （88.00%） were observed in experimental Ⅰ group and experimental Ⅴ group, respectively. Under the experimental condition （basal diet containing 0.80% of lysine） of this study, the recommended dietary lysine and sulfur amino acid ratio for Rex Rabbit in late fattening period was （ 1：0.8）-（1：0.9）.