Abstract: [Objective]To study the effects of compound small peptide preparation on productive performance,morbidity and mortality of broilers,and to provide technical support for its scientific application in broiler production.[Method]A total of 1 200 healthy Ross 308 broilers aged 28 days with the similar weight were randomly divided into four groups,each with four replicates and 75 chickens per replicate.The control group fed a basal diet with no addition of the compound small peptide preparation,and the experimental group 1,2 and 3 fed a basal diet supplemented with 2.0%,2.5% and 3.0% compound small peptide preparation,respectively.[Result]The dietary supplementation of compound small peptide preparation significantly increase the final weight and average daily gain of broilers (P<0.05 or P<0.01),and significantly reduce the feed-weight ratio,diarrhea rate,and morbidity and mortality associated with respiratory diseases (P<0.05 or P<0.01).[Conclusion]The compound small peptide preparation can significantly improve the productive performance and health status of broilers,and the recommended dietary supplementation level is 2.5%-3.0%.