[1] LEE E H,BAEK S Y,PARK J Y,et al.Emodin in Rheum undulatum inhibits oxidative stress in the liver via AMPK with Hippo/Yap signalling pathway[J]. Pharmaceutical Biology,2020,58(1):333-341. [2] SONG P X,ZHANG R J,WANG X X,et al.Dietary grape-seed procyanidins decreased postweaning diarrhea by modulating intestinal permeability and suppressing oxidative stress in rats[J].Journal of Agricultural and Food Chemistry,2011,59(11):6227-6232. [3] KOJONAZAROV B,NOVOYATLEVA T,BOEHM M,et al.p38 MAPK inhibition improves heart function in pressure-loaded right ventricular hypertrophy[J]. American Journal of Respiratory Cell and Molecular Biology, 2017,57(5):603-614. [4] CHANG L,KARIN M.Mammalian MAP kinase signalling cascades[J].Nature,2001,410(6824):37-40. [5] ROUX P P,BLENIS J.ERK and p38MAPK-activated protein kinases:a family of protein kinases with diverse biological functions[J].Microbiology and Molecular Biology Reviews,2004,68(2):320-344. [6] BREWSTER J L,DE VALOIR T,DWYER N D,et al.An osmosensing signal transduction pathway in yeast[J].Science,1993,259(5120):1760-1763. [7] 高琳,汤月霞,姚睿荣,等.兔颈动脉外膜损伤术后氧化应激中p38MAPK的表达变化[J].心脏杂志,2009,21(5):615-620. [8] 迟倩茹. 基于MAPKs/NF-κB途径探究H2S暴露致肉鸡脾脏程序性坏死的分子机制[D].哈尔滨:东北农业大学,2019. [9] 周吉,陈硕,邹圣强.p38MAPK-Nrf2-HO-1信号通路在大鼠机械通气所致肺损伤中作用的研究[J].中华灾害救援医学,2020,8(10):554-558. [10] 叶任之. 清达颗粒通过调控p38MAPK/Nrf2/HO-1通路减轻脂多糖诱导的小胶质细胞氧化应激反应[D].福州:福建中医药大学,2020. [11] SUN L,XU G Q,DONG Y Y Y,et al. Quercetin protects against lipopolysaccharide-induced intestinal oxidative stress in broiler chickens through activation of Nrf2 pathway[J].Molecules,2020,25(5):1053. [12] ZHANG H B,YUAN B,HUANG H F.Gastrodin induced HO-1 and Nrf2 up-regulation to alleviate H2O2-induced oxidative stress in mouse liver sinusoidal endothelial cells through p38MAPK phosphorylation[J].Brazilian Journal of Medical and Biological Research,2018,51(10):e7439. [13] WANG Y J,WANG X Y,HAO X Y,et al.Ethanol extract of Centipeda minima exerts antioxidant and neuroprotective effects via activation of the Nrf2 signaling pathway[J].Oxidative Medicine and Cellular Longevity,2019,4(3):9421037. [14] KEN I,WAKABAYASHI N,KATOH Y,et al.Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain[J].Genes and Development,1999,13(1):76-86. [15] WAKABAYASHI N,ITOH K,WAKABAYASHI J,et al.Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation[J].Nature Genetics,2003,35(3):238-245. [16] JAIN A K,JAISWAL A K.GSK-3β acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2[J].Journal of Biological Chemistry,2007,282(22):16502-16510. [17] 李延森,李照见,贾潇潇,等.环境高温诱导巴马香猪睾丸细胞凋亡并激活Nrf2/HO-1抗氧化信号通路[J].畜牧兽医学报,2018,49(6):1154-1162. [18] 王换换,申正杰,肖航,等.热应激对肝脏中Keap1-Nrf2信号通路及下游基因表达的影响[J].南京农业大学学报,2017,40(1):151-156. [19] 薛菠. EGCG对热应激肉鸡生长性能和抗氧化性能的影响[D].武汉:长江大学,2018. [20] 李丽. 鸡持续冷应激启动Nrf2抗氧化信号转导路径的研究[D].合肥:安徽农业大学,2013. [21] 贾红豆. 热休克蛋白B7在酮病奶牛脂肪组织氧化应激中的作用研究[D].长春:吉林大学,2019. [22] 朱士勇. Nrf2抗氧化防御应答在镉致鸡胚神经管发育异常中的作用[D].哈尔滨:东北农业大学,2017. [23] 葛晶. Nrf2介导抗氧化防御与UPRmt在镉致鸡肾脏线粒体损伤中的作用[D].哈尔滨:东北农业大学,2018. [24] 王菲. 锌对热暴露小鼠和巴马香猪肝脏氧化应激的影响[D].南京:南京农业大学,2015. [25] 王中成. 果胶寡糖螯合锌对肉仔鸡生长调控机制的研究[D].北京:中国农业科学院,2019. [26] 肖雪. 硒代蛋氨酸与亚硒酸钠调控肉鸡抗氧化功能的差异及其机制研究[D].杭州:浙江大学,2017. [27] SHI H Y,YAN S M,GUO Y M,et al.Vitamin A pretreatment protects NO-induced bovine mammary epithelial cells from oxidative stress by modulating Nrf2 and NF-κB signaling pathways[J].Journal of Animal Science,2018,96(4):1305-1316. [28] 李黎云. 日粮添加阿魏酸与VE对育肥猪肉品质和抗氧化性能的影响[D].南京:南京农业大学,2013. [29] 崔艳军. 热应激和氧化应激对肥育猪骨骼肌代谢的影响及硫辛酸的调控作用[D].北京:中国农业科学院,2016. [30] 徐群,黄华山,王英楠,等.维生素在畜禽生产中应用的研究进展[J].山东畜牧兽医,2020,41(9):88-91. [31] SUN Y W,WU Y J,WANG Z L,et al.Dandelion extract alleviated lipopolysaccharide-induced oxidative stress through the Nrf2 pathway in bovine mammary epithelial cells[J].Toxins,2020,12(8):496. [32] 王凤鸽. 黄芪甲苷对氨诱导的奶牛乳腺上皮细胞氧化应激和凋亡的缓解作用及其机制研究[D].长春:吉林大学,2019. [33] 蒋红琴. 番茄红素对巴美肉羊肉品质的影响及其抗氧化机理研究[D].北京:中国农业大学,2015. [34] 叶舒. 白藜芦醇对FLHS蛋鸡肝脏氧化应激及炎症的调控作用[D].南昌:江西农业大学,2017. [35] 缪福俊,宁德鲁.核桃多酚类物质生物活性研究进展[J].中国油脂,2021,46(1):48-51. [36] 叶舒,李美东,罗凯,等.植物多糖生物活性功能研究进展[J].湖北农业科学,2020,59(24):5-8. [37] 张晓萌,王圆圆,王洪晶.中药材黄酮类化合物的研究进展[J].广东化工,2020,47(24):55-56. [38] OLIVER K M,GARVEY J F,NG C T,et al.Hypoxia activates NF-κB-dependent gene expression through the canonical signaling pathway[J].Antioxidants and Redox Signaling,2009,11(9):2057-2064. [39] KARIN M.How NF-kappaB is activated: the role of the IkappaB kinase (IKK)complex[J].Oncogene,1999,18(49):6867-6874. [40] GRETEN F R,KARIN M.The IKK/NF-κB activation pathway-a target for prevention and treatment of cancer[J].Cancer Letters,2004,206(2):193-199. [41] 张梦龙. HSP27通过抗氧化应激及细胞凋亡途径调控奶牛RFM发生作用机制的研究[D].大庆:黑龙江八一农垦大学,2020. [42] 闫晓霞,谢丽君,刘欢欢,等.氧化应激对PRRSV体外感染PAMs后诱导TLR3/NF-κB信号通路相关蛋白的影响[J].中国兽医学报,2016,36(11):1916-1922. [43] MONTILLA S I R,JOHNSON T P,PEARCE S C,et al. Heat stress causes oxidative stress but not inflammatory signaling in porcine skeletal muscle[J].Temperature,2014,1(1):42-50. [44] 史晓霞. NEFAs和BHBA诱导氧化应激对奶牛肝细胞NF-κB信号通路影响的研究[D].长春:吉林大学,2014. [45] 李兰芝. 棕榈酸、β-羟丁酸诱导氧化应激对牛子宫内膜细胞NF-κB信号通路影响的研究[D].沈阳:沈阳农业大学,2019. [46] 苏芮. 硒通过Nrf2/GPX1-PPARγ-NF-κB信号通路对一氧化氮诱导的奶牛乳腺上皮细胞氧化应激的减缓作用[D].呼和浩特:内蒙古农业大学,2019. [47] FUSCO R,CORDARO M,SIRACUSA R,et al.Consumption of Anacardium occidentale L. (cashew nuts) inhibits oxidative stress through modulation of the Nrf2/HO-1 and NF-κB pathways[J].Molecules,2020,4426(25):1-18. [48] LEE S G,BROWNMILLER C R,LEE S O,et al.Anti-inflammatory and antioxidant effects of anthocyanins of Trifolium pratense (Red Clover) in lipopolysaccharide-stimulated RAW-267.4[J].Macrophages,2020,12(4):1089. [49] 谢婉秋. 黄芪多糖通过MDA5/NF-κB信号通路抑制染镉雏鸡外周血液淋巴细胞损伤作用的研究[D].哈尔滨:东北农业大学,2018. [50] BASELGA-ESCUDERO L,BLADE C,RIBAS-LATRE A,et al.Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells[J].Nucleic Acids Research,2014,42(2):882-892. [51] JIANG Y,GRAM H,ZHAO M,et al.Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases,p38δ[J].Journal of Biological Chemistry,1997,272(48):30122-30128. |