附睾中非编码小RNA（sncRNA）的研究进展

doi:10.12160/j.issn.1672-5190.2023.02.010

Abstract

Abstract:

Small non-coding RNA （sncRNA） functions primarily through inhibitory regulation of target genes. Recent research revealed that sncRNA is expressed in various parts of the mammalian epididymis and plays a crucial role in regulating gene expression in different segments of the epididymis. The diversity of sncRNA identified in epididymal epithelial cells and the spatiotemporal variations in sncRNA expression level may have an impact on many potential target genes, regulating the physiological functions of epididymis. In addition, these sncRNA can also be transmitted to sperm through epididymosomes, producing a series of regulatory effects on sperm. This paper reviews the research progress of the expression of sncRNA in epididymis as well as the regulation of sncRNA on epididymis function and sperm function in epididymis, in hoping to provide references for exploring the molecular mechanism of the regulatory effect of sncRNA on male germ cells.

Key words: small non-coding RNA, target gene, epididymis, epididymosomes, sperm

CLC Number:

Q78
Q492.4

XU Jiaoxia, ZHANG Jiaxin, ZHOU Xuan, HE Xiaolong. Research Progress of Small Non-coding RNA（sncRNA）in Epididymis[J]. Animal Husbandry and Feed Science, 2023, 44(2): 61-65.

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Research Progress of Small Non-coding RNA（sncRNA）in Epididymis

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