腺苷酸活化蛋白激酶在奶牛疾病中的作用研究进展

doi:10.12160/j.issn.1672-5190.2022.06.002

Abstract

Abstract:

The incidence of mastitis, ketosis, fatty liver and some other diseases in dairy cow farming has increased year after year as large-scale and intensive dairy cow farming improved. As an energy receptor, AMP-activated protein kinase （AMPK） reflects the energy state of cells. AMPK plays crucial roles in glucose, lipid and protein metabolism as well as in mitochondrial biogenesis and autophagy. AMPK is thought to be a potential intervention or treatment target for a variety of diseases and has been extensively studied in metabolic diseases of dairy cows. This paper reviews the research progress on regulative roles of AMPK in dairy cow mastitis, ketosis and fatty liver, in hoping to provide references for targeted treatment of these diseases.

Key words: AMP-activated protein kinase, mastitis, fatty liver, ketosis, milk fat synthesis

CLC Number:

S858.232.2

DOU Wen-li, Baohua , CAO Pei-pei, SUN Yi-shuo, LIU Ji-guo, YANG Wen-fei, MA Yun, MA Yan-fen. Research Progress on Roles of AMP-activated Protein Kinase in Dairy Cow Diseases[J]. Animal Husbandry and Feed Science, 2022, 43(6): 6-13.

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Research Progress on Roles of AMP-activated Protein Kinase in Dairy Cow Diseases

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