Abstract: [Objective] The aim was to establish an efficient and environmental protection extraction process of the Baphicanthus co-mpound feed additives. [Method] Ultrasonic extraction was used as an assistant method, and then the extraction solvent, extraction time, liquid ratio and extraction times in extraction process of the Baphicanthus compound feed additives were investigated by using L9（34） orthogonal design. The gain ratio of dried extract, total content of adenosine and total content of chlorogenic acid were taken as the quantitative indexes. [Result] The best extraction condition of Baphicanthus compound feed additives was as followed： 16 times amount of 50% ethanol was added and then extracted for two times, with 45 min for each time. [Conclusion] The optimized extraction technology is simple, stable, reproducible and good for large-scale production. The research provides basis for the extraction process of the Baphicanthus compound feed additives.