Abstract: [Objective]To assess the therapeutic effect of salicylic acid on pododermatitis in dairy cow. [Method]A total of 45 dairy cows clinically diagnosed as pododermatitis were selected and randomly assigned into the following three groups a negative control group （n=5） received no treatment, an antimicrobial control group （n=20） received administration of lincomycin, and a salicylic acid treatment group （n=20） received 40% salicylic acid ointment. To evaluate the therapeutic effect, the dairy cows were subjected to lameness scoring and skin pain scoring on the 0, 3^rd, 14^th, and 30^th day of the administration, respectively.[Result]On the 3^rd day of administration, no fully recovered cases were observed in the antimicrobial control group and salicylic acid treatment group, and the symptom of lameness was obviously alleviated after treatment. On the 14^th day of administration, the cure rate of salicylic acid treatment group was 45%, which was obviously higher than that of the antimicrobial control group （25%）, and the effective rate was 75%, which was higher than that of the antimicrobial control group （60%）. On the 30^th day of administration, the effective rate of salicylic acid treatment group was 65%, which was higher than that of the antimicrobial control group （55%）.[Conclusion]Salicylic acid has a good clinical therapeutic effect and can be used as alternative medicine for the treatment of pododermatitis in dairy cow.

Key words: dairy cow, pododermatitis, salicylic acid, therapeutic effect