伪狂犬病毒囊膜糖蛋白gC的研究进展

doi:10.12160/j.issn.1672-5190.2019.07.026

Abstract

Abstract: Pseudorabies virus （PRV） infection can cause large-scale death in pigs and bring huge economic losses to the pig industry. The live attenuated vaccines and inactivated vaccines are widely used in prevention of pseudorabies in pigs. While the gene of envelope glycoprotein gC of PRV is a non-essential gene for viral proliferation, the PRV lacking of the gC gene cannot effectively adhere to the surface of the target cell. The structure and function of the envelope glycoprotein gC of PRV and its application in vaccine development were reviewed, in hoping to provide basis for the prevention and control of pseudorabies.

Key words: pseudorabies virus, envelope glycoprotein gC, vaccine

CLC Number:

WEI Jin-feng, YANG Kang-li, XU Zheng, HOU Lei-lei, WANG Yan-hui. Research Advances in Envelope Glycoprotein gC of Pseudorabies Virus[J]. Animal Husbandry and Feed Science, 2019, 40(7): 101-104.

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Research Advances in Envelope Glycoprotein gC of Pseudorabies Virus

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