中草药通过成骨和成血管特性改善肉鸡骨骼健康的研究进展

doi:10.12160/j.issn.1672-5190.2025.06.012

摘要/Abstract

摘要： 骨骼健康是影响肉鸡健康和产业发展的重要因素之一。在集约化养殖中,肉鸡的快速增长会引发一系列的骨骼问题,降低肉鸡的生产性能,严重制约其产业的发展。在肉鸡骨骼生长发育过程中血管生成与骨生成高度耦合,两者功能正常与否对骨骼健康至关重要。中草药作为一种天然药物,具有绿色、无残留、耐药风险小等优点,在预防和治疗骨骼疾病等方面具有广阔的应用前景。已有研究表明,中草药及其活性成分可以通过调节骨代谢、骨免疫和血管生成,进而改善骨骼健康。综述了肉鸡骨生成与骨血管生成的调控机制,总结了骨碎补、巴戟天、蛇床子、黄芪等单味或复方中草药及其活性成分通过成骨及成血管特性发挥骨骼保护作用的机制,分析了中草药在肉鸡骨骼健康上的应用优势及挑战,以期为中草药用于肉鸡骨骼健康的维护提供理论依据。

关键词: 中草药, 肉鸡, 骨骼生长发育, 骨血管生成, 骨代谢, 骨免疫

Abstract: Bone health is one of the important factors influencing broiler health and the sustainable development of the poultry industry. Under intensive farming conditions, the rapid growth of broilers can lead to a range of skeletal problems, which reduce production performance and severely restrict industry development. During skeletal development in broilers, angiogenesis and osteogenesis are closely coupled, and their proper functioning is crucial for bone health. As natural products, Chinese herbal medicines with the advantages of green, residue-free, and posing a low risk of drug resistance, holding broad application prospects for the prevention and treatment of skeletal diseases. Studies have shown that Chinese herbal medicines and their active components can improve bone health by regulating bone metabolism, bone immunity, and angiogenesis. This review outlines the regulatory mechanisms of osteogenesis and bone angiogenesis in broilers, summarizes the bone-protective mechanisms of single-herb or compound formulations, such as Drynaria fortunei, Morinda officinalis, Cnidium monnieri, Astragalus membranaceus and their active constituents through osteogenic and angiogenic properties, and analyzes the advantages and challenges of applying Chinese herbal medicines to broiler bone health. The aim is to provide a theoretical basis for the use of Chinese herbal medicines in maintaining skeletal health in broilers.

Key words: Chinese herbal medicines, broilers, skeletal growth and development, bone angiogenesis, bone metabolism, bone immunity

中图分类号:

闫树棋, 翟曼佳, 陈琪瑶, 岳涛静, 路亚男, 王丽, 黄淑成. 中草药通过成骨和成血管特性改善肉鸡骨骼健康的研究进展[J]. 畜牧与饲料科学, 2025, 46(6): 85-94.

YAN Shuqi¹, ZHAI Manjia¹, CHEN Qiyao¹, YUE Taojing¹, LU Ya′nan¹, WANG Li², HUANG Shucheng¹. Research Progress of Chinese Herbal Medicine to Improve Broilers Bone Health via Osteogenic-Angiogenic Properties[J]. Animal Husbandry and Feed Science, 2025, 46(6): 85-94.

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