Abstract: Symptoms of mycotoxin poisoning appeared in some scale pig farm in April 2012, such as a significant reduction of the conception rate in gilts, litter size and healthy litter size. Through preliminary investigation, it was found that the feed in the farm had been polluted by mycotoxin, so types and contents of mycotoxins in raw maize and feed samples were determined by HPLC. Results showed that zearalenone, vomitoxin and mycotoxin in raw maize were excessive. The reproductive performance of sow was significantly recovered by changing feed and using anti-mildew agent.