Abstract: In the teaching process of Biostatistics,the practical application should be set as the fundamental teaching thought;according to the orientation of the training goal of different specialties,the undergraduates should be taught in accordance with their aptitude,the educational idea should be updated,the practical training should be enhanced,and the teaching methods and means should be reformed and explored.Via the constantly reform and exploration,the undergraduates will obtain basic quality in scientific research,such as data collecting,collating,analyzing and even scientific conclusions drawing,which will lay a solid theoretical foundation for their future participation in scientific research.