Abstract: Research-university plays an important role in the production and transformation process of knowledge. The teachers in Jilin University,as a research-university,must focus on the key issue that how to build veterinary medicine specialty well to make it more useful in clinical application and more competitive in basic research. In order to meet the need of research-university,the research aspects of basic veterinary medicine specialty were optimized and integrated into four characteristic aspects like stransgenic animal,molecular pathology and animal models for animal serious epidemic disease,regulation of animal growth and development,and molecular pharmacology of antibacterial agents. The position and research contents of basic veterinary medicine specialty were explored,furthermore the reforming experiences of integrated professional teaching and related experiments were discussed.