Abstract: Cell engineering is a subject with stronger practicality and comprehensiveness. Its traditional teaching methods and means were unitary, which was unfavorable for developing the teaching level of teachers and cultivating the innovation ability of students. The teaching content was adjusted and renovated and the practice and experimental taehes were strengthened. The teachers＇ quality was optimized and the master consciousness of students was excitated by using modem teaching means, so as to fully mobilize the enthusiasm of teachers and students. The importance of the teaching reform in the course teaching of Cell Engineering was discussed, so as to lay the foundation for perfecting this teaching reform further and provide references for the theory and practice teaching of Cell Engineering course in other universities.