Abstract: ＂Problem-solving＂ teaching method is a teaching approach by which attentions were paid to cultivate the ability of solving the practical problem. This method was applied in the experiment teaching practice of Instrumental Analysis. The experimental course of Instrumental Analysis was reformed and designed by determining the experimental items, preparation before class, making the assessment score table, so as to enhance the practical ability of students. The application situations of ＂problem-solving＂ teaching method in the experimental teaching of Instrumental Analysis were discussed.