Abstract: Animal Pathological A natomy is an important professional basic course of the veterinary medicine specialty with strong theoretical and practical property. In order to meet the cultivation requirements for undergraduates in universities and colleges and to improve the teaching quality of this course, PBL teaching method is introduced to classroom teaching. The application of PBL teaching mode in teaching of Animal Pathological Anatomy is discussed： the clinical cases are served as the guidance; the related problems are served as the main line; the interaction between teachers and undergraduates are implemented, the learning enthusiasm of the undergraduates is improved, and their problem solving ability is cultivated.