Abstract: The aims of classroom teaching for postgraduates are expected to cultivate their capacity of self-learning, creative thinking, critical thinking and teamwork. At present, the traditional teaching methods still play the dominant role in classroom teaching for postgraduates, which is unfavorable for cultivating high-quality professionals. Therefore, it is imperative to innovate and reform the classroom teaching methods for postgraduates. The seminar-based teaching (SBT) and team-based learning (TBL) are the recently developed and student-centered teaching methods. They both have their own advantages and disadvantages but are complementary. This article evaluated the effect of combinative application of SBT and TBL in teaching of Cell Molecular Biology for postgraduates. The results showed that the SBT and TBL integrated teaching method significantly improved the self-learning motivation and independent-thinking enthusiasm, and enhanced the innovative sense and teamwork ability of postgraduates, indicating that the combinative application of SBT and TBL improved the comprehensive quality of scientific research of postgraduates.